Nonspecific Enhancement of Resistance to Bacterial Infection

Nonspecific resistance to bacterial infections. Enhancement by ubiquinone-8

A lipid fraction from Escherichia coli was extracted with apolar solvents and was found to protect mice from a number of experimental bacterial infections. The benzoquinone, ubiquinone-8, was isolated from this extract by high pressure liquid chromatography and identified as such by nuclear magnetic resonance and mass spectrometry. At a dose of 25 mg/kg this substance was found to provide compl...

Interleukin-l-Induced Nonspecific Resistance to Bacterial Infection in Mice Is Not Mediated by Glucocorticosteroids

Interleukin-l-Induced Nonspecific Resistance to Bacterial Infection in Mice Is Not Mediated by Glucocorticosteroids

Interleukin-l-Induced Nonspecific Resistance to Bacterial Infection in Mice Is Not Mediated by Glucocorticosteroids

Symposium on bacterial endotoxins. II. Possible mechanisms whereby endotoxins evoke increased nonspecific resistance to infection.